Rintze M. Zelle bio photo

Rintze M. Zelle

Scientist in biotechnology, Citation Style Language-developer.

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Scientific publications


  1. Froehlich, A., Henningsen, B., Covalla, S., & Zelle, R. M. (2018). Mutations in iron-sulfur cluster proteins that improve xylose utilization. US9920312B2.
  2. Oeser, M., Henningsen, B., Fisher, J., Rice, C. F., Froehlich, A., Argyros, A., & Zelle, R. M. (2017). Regulation Of The Ras/camp/pka Signaling Pathway In Yeasts. WO2017158189A1.
  3. Henningsen, B. M., Hon, S., Covalla, S. F., Sonu, C., Argyros, D. A., Barrett, T. F., … Zelle, R. M. (2015). Increasing anaerobic acetate consumption and ethanol yield in Saccharomyces cerevisiae with NADPH-specific alcohol dehydrogenase. Applied and Environmental Microbiology, 81(23), 8108–8117. doi:10.1128/AEM.01689-15 (PDF, full-text) (PDF, supplemental file) (AEM spotlight)
  4. Zelle, R. M., Shaw, A. J., & van Dijken, J. P. (2014). Method for acetate consumption during ethanolic fermentation of cellulosic feedstocks. WO2014074895. PDF (9 MB file)
  5. Zelle, R. M. (2011). Metabolic engineering of Saccharomyces cerevisiae for C4-dicarboxylic acid production (PhD thesis). Delft University of Technology, Delft, the Netherlands. PDF
  6. Zelle, R. M., Harrison, J. C., Pronk, J. T., & van Maris, A. J. A. (2011). Anaplerotic role for cytosolic malic enzyme in engineered Saccharomyces cerevisiae strains. Applied and Environmental Microbiology, 77(3), 732–738. doi:10.1128/AEM.02132-10 PDF
  7. Lawrence, A., Pronk, J. T., van Maris, A. J. A., Zelle, R. M., Madden, K. T., Harrison, J. C., … Bower, S. (2010). Methods and microorganisms for production of C4-dicarboxylic acids. WO2010111344. PDF (23 MB file)
  8. Zelle, R. M., Trueheart, J., Harrison, J. C., Pronk, J. T., & van Maris, A. J. A. (2010). Phosphoenolpyruvate carboxykinase as the sole anaplerotic enzyme in Saccharomyces cerevisiae. Applied and Environmental Microbiology, 76(16), 5383–5389. doi:10.1128/AEM.01077-10 PDF
  9. Zelle, R. M., Hulster, E. de, Kloezen, W., Pronk, J. T., & van Maris, A. J. A. (2010). Key process conditions for production of C4 dicarboxylic acids in bioreactor batch cultures of an engineered Saccharomyces cerevisiae strain. Applied and Environmental Microbiology, 76(3), 744–750. doi:10.1128/AEM.02396-09 PDF
  10. Abbott, D. A., Zelle, R. M., Pronk, J. T., & van Maris, A. J. A. (2009). Metabolic engineering of Saccharomyces cerevisiae for production of carboxylic acids: current status and challenges. FEMS Yeast Research, 9(8), 1123–1136. doi:10.1111/j.1567-1364.2009.00537.x
  11. Zelle, R. M., de Hulster, E., van Winden, W. A., Waard, P. de, Dijkema, C., Winkler, A. A., … van Maris, A. J. A. (2008). Malic acid production by Saccharomyces cerevisiae: engineering of pyruvate carboxylation, oxaloacetate reduction, and malate export. Applied and Environmental Microbiology, 74(9), 2766–2777. doi:10.1128/AEM.02591-07 PDF

Acknowledged in

  1. De Kok, S., Meijer, J., van Loosdrecht, M. C. M., & Kleerebezem, R. (2013). Impact of dissolved hydrogen partial pressure on mixed culture fermentations. Applied Microbiology and Biotechnology, 97(6), 2617–2625. doi:10.1007/s00253-012-4400-x (editing and proofreading)
  2. Van den Brink, J., Akeroyd, M., van der Hoeven, R., Pronk, J. T., de Winde, J. H., & Daran-Lapujade, P. (2009). Energetic limits to metabolic flexibility: responses of Saccharomyces cerevisiae to glucose–galactose transitions. Microbiology, 155(4), 1340–1350. doi:10.1099/mic.0.025775-0 (assistance with experimental work)
  3. Harris, D. M., van der Krogt, Z. A., Klaassen, P., Raamsdonk, L. M., Hage, S., van den Berg, M. A., … Daran, J.-M. (2009). Exploring and dissecting genome-wide gene expression responses of Penicillium chrysogenum to phenylacetic acid consumption and penicillinG production. BMC Genomics, 10(1), 75. doi:10.1186/1471-2164-10-75 (assistance with bioinformatics analysis)

Peer review

As of August 2017, I have refereed a total of 35 manuscripts for the following journals (see also my Publons profile):